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In the United States, the prevalence of severeHA in adults (?18 years of age) is reported to be between 16% and 26%, with a reportedworldwide incidence of 8% to 18% (361, 362).

pimprina and developedby Hindustan Antibiotics at Pimpri. In a study in 20 hip replacement patients ana-lyzed by LC–MS/MS and population PK analysis isotretinoin on line the bone-to-serum AUC ratios were0.20 (10th–90th percentile for between-patient variability 0.16–0.25) for cortical and 0.18(0.11–0.29) for cancellous bone [12].

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