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Uncontrolled high PEEP pro-duction associated with inappropriately high oxy-gen ? ows through prongs or catheters may lead togastric distension or pneumothorax. Irrigationof the catheter can flush out clots that can increasespasms. Neither haloperidol nor risperidone is regis-tered for use in childhood delirium despite thefact that both drugs are frequently used for thisreason in the adult population. In both groups, function and quality of life improved, though in all cases theimprovement was statistically greater in patients who underwent TAA. Although the majority of mutant p53 studiessuggest that the presence of mutant p53 reduces sensitivity to chemotherapy orradiation, there are many studies that show no effect or show the opposite effect;that is, that mutant p53 enhances sensitivity to these agents

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