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Important amongthese are ginkgolide B (from a Chinese plant), and somestructural analogues of PAF.The PAF antagonists have manyfoldtherapeutic potentials like treatment of stroke, intermittentclaudication, sepsis, myocardial infarction, shock, g.i.ulceration, asthma and as contraceptive. Both ventilationand oxygenation were signi?cantly improvedwith PaCO2 decreasing from 47 ± 3 mmHg to39 ± 11 mmHg and PaO2 increasing from 105 ± 8to 171 ± 12 mmHg after transition to VDR whilepeak in?ation pressures (PIP) dropped from 52 ± 2to 38 ± 2 cm H2O (Rodeberg et al. (2000) The medial temporal lobe,the hippocampus and the memory systems of the brain.

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